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Summary Read the full fact sheet. On this page. Tuberculosis, commonly known as TB, is an infectious disease caused by infection with the Mycobacterium tuberculosis bacterium. Typically TB affects the lungs but it can also infect any other organ of the body. It is spread from person to person through the air when someone with an active infection of the lungs or throat coughs, sings, laughs or sneezes.
Most people infected with TB do not have any symptoms although there is a 10 per cent lifetime risk that symptoms will develop later into an active infection.
In people without symptoms, medications can help reduce the risk of the infection developing into active disease. People who are young or elderly or who have weakened immune systems are more prone to active infection. TB was once the leading cause of death in many countries but, due to effective treatment and prevention programs, it is now uncommon in the Australian-born population.
Causes of TB TB is spread when a person with an active disease of the lungs or upper airways nose and throat coughs, sings, laughs or sneezes. People nearby may breathe in the exhaled bacteria and become infected.
The bacteria can settle in the lungs and begin to grow. From there, the bacteria can move through the blood or lymphatic system to other parts of the body such as the kidney, spine and brain. Although TB infection in the lungs or throat can be spread to other people, TB in other parts of the body is usually not infectious. An infected person who does not have active disease cannot transmit TB to another person.
It's important to take the medicine for active TB for at least 6 months. Almost all people are cured if they take their medicine just like their doctors say to take it.
If tests still show active TB after 6 months, then treatment continues for another 2 or 3 months. If the TB bacteria are resistant to several antibiotics multidrug-resistant TB , then treatment may be needed for a year or longer.
Most of the time, one antibiotic is used to treat latent TB infection. This type of infection cannot be spread to others but can develop into active TB disease.
The antibiotic usually is taken for 4 to 9 months. Or more than one antibiotic may be taken once a week for 3 months. If you miss doses of your medicine, or if you stop taking your medicine too soon, your treatment may fail or have to go on longer. You may have to start your treatment over again. This can also cause the infection to get worse or may lead to an infection that is resistant to antibiotics. This is much harder to treat. TB can only be cured if you take all the doses of your medicine.
A doctor or nurse may have to watch you take it to make sure that you never miss a dose and that you take it the proper way. You may have to go to the doctor's office every day. Or a nurse may come to your home or work. This is called direct observational treatment. It helps people follow all of the instructions and keep up with their treatment, which can be complex and take a long time.
Cure rates for TB have greatly improved because of this type of treatment. If active TB is not treated, it can damage your lungs or other organs and can be deadly.
You can also spread TB by not treating active TB. Tuberculosis TB is caused by Mycobacterium tuberculosis , slow-growing bacteria that thrive in areas of the body that are rich in blood and oxygen, such as the lungs. If you have latent tuberculosis TB , you do not have symptoms and cannot spread the disease to others. If you have active TB, you do have symptoms and can spread the disease to others.
Which specific symptoms you have will depend on whether the bacteria are in your lungs the most common site or in another part of your body extrapulmonary TB. There are other conditions with symptoms similar to TB, such as pneumonia and lung cancer. Symptoms of active TB in the lungs begin gradually and develop over a period of weeks or months.
You may have one or two mild symptoms and not even know that you have the disease. Symptoms of TB outside the lungs extrapulmonary TB vary widely depending on which area of the body is infected. For example, back pain can be a symptom of TB in the spine, or your neck may get swollen when lymph nodes in the neck are infected.
Tuberculosis TB develops when Mycobacterium tuberculosis bacteria are inhaled into the lungs. The infection usually stays in the lungs. But the bacteria can travel through the bloodstream to other parts of the body extrapulmonary TB. An initial primary infection can be so mild that you don't even know you have an infection.
In a person who has a healthy immune system, the body usually fights the infection by walling off encapsulating the bacteria into tiny capsules called tubercles.
The bacteria remain alive but cannot spread to surrounding tissues or other people. This stage is called latent TB, and most people never go beyond it. A reaction to a tuberculin skin test is how most people find out they have latent TB. It takes about 48 hours after the test for a reaction to develop, which is usually a red bump where the needle went into the skin.
Or you could have a rapid blood test that provides results in about 24 hours. If a person's immune system becomes unable to prevent the bacteria from growing, the TB becomes active. Active TB in the lungs pulmonary TB is contagious. TB spreads when a person who has active disease exhales air that contains TB-causing bacteria and another person inhales the bacteria from the air. These bacteria can remain floating in the air for several hours. Coughing, sneezing, laughing, or singing releases more bacteria than breathing.
In general, after 2 weeks of treatment with antibiotics, you cannot spread active pulmonary TB to other people. Skipping doses of medicine can delay a cure and cause a relapse. In these cases, you may need to start treatment over. Relapses usually occur within 6 to 12 months after treatment.
Not taking the full course of treatment also allows antibiotic-resistant strains of the bacteria to develop, making treatment more difficult. Without treatment, active TB can cause serious complications, such as:. Active TB in parts of the body other than the lungs extrapulmonary TB is not spread easily to other people. You take the same medicines that are used to treat pulmonary TB.
You may need other treatments depending on where in your body the infection is growing and how severe it is. People are at increased risk of infection with tuberculosis TB when they:. People who have an infection that cannot spread to others latent TB infection are at risk of developing active TB if they:.
Call your doctor immediately if you have:. Your family doctor or general practitioner can help you find out if you have tuberculosis TB. For treatment of active TB, which can be spread to others, or to treat complications of TB, you may be referred to:.
Doctors diagnose active tuberculosis TB in the lungs pulmonary TB by using a medical history and physical examination, and by checking your symptoms such as an ongoing cough, fatigue, fever, or night sweats. Doctors will also look at the results of a:. Diagnosing TB in other parts of the body extrapulmonary TB requires more testing. Tests include:.
You may also have a blood test for hepatitis. During treatment, a sputum culture is done once a month—or more often—to make sure that the antibiotics are working. You may have a chest X-ray at the end of treatment to use as a comparison in the future.
You may have tests to see if TB medicines are harming other parts of your body. These tests may include:. Public health officials encourage screening for people who are at risk for getting TB. Doctors treat tuberculosis TB with antibiotics to kill the TB bacteria. These medicines are given to everyone who has TB, including infants, children, pregnant women, and people who have a weakened immune system.
Health experts recommend: footnote 7 footnote 4. Treatment is recommended for anyone with a skin test that shows a TB infection, and is especially important for people who:. Treatment for tuberculosis in parts of the body other than the lungs extrapulmonary TB usually is the same as for pulmonary TB. You may need other medicines or forms of treatment depending on where the infection is in the body and whether complications develop.
You may need treatment in a hospital if you have:. If treatment is not successful, the TB infection can flare up again relapse. People who have relapses usually have them within 6 to 12 months after treatment. Treatment for relapse is based on the severity of the disease and which medicines were used during the first treatment. Active tuberculosis TB is very contagious. But this vaccination is almost never used in North America because:. Home treatment for tuberculosis TB focuses on taking the medicines correctly to reduce the risk of developing multidrug-resistant TB.
During treatment for TB, eat healthy foods and get enough sleep and some exercise to help your body fight the infection. If you are losing too much weight, eat balanced meals with enough protein and calories to help you keep weight on. If you need help, ask to talk with a registered dietitian. Because TB treatment takes so long, it is normal to:. Your doctor or health department can help you find a counsellor or social worker to help you cope with your feelings.
Several antibiotics are used at the same time to treat active tuberculosis TB disease. For people who have multidrug-resistant TB, treatment may continue for as long as 24 months. These antibiotics are given as pills or injections. TB disease that occurs in parts of your body other than the lungs extrapulmonary TB usually is treated with the same medicines and for the same length of time as active TB in the lungs pulmonary TB. But TB throughout the body miliary TB or TB that affects the brain or the bones and joints in children may be treated for at least 12 months.
Corticosteroid medicines also may be given in some severe cases to reduce inflammation. They may be helpful for children at risk of central nervous system problems caused by TB and for people who have conditions such as high fever, TB throughout the body miliary TB , pericarditis , or peritonitis.
One antibiotic usually is used to treat latent TB infection, which cannot be spread to others but can develop into active TB disease. For this treatment, a health professional may watch you take each dose of antibiotics. Taking every dose of antibiotic helps prevent the TB bacteria from getting resistant to the antibiotics. Multiple-drug therapy to treat TB usually involves taking four antibiotics at the same time. This is the standard treatment for active TB.
If you miss doses of medicine or you stop treatment too soon, your treatment may go on longer or you may have to start over. This can also cause the infection to get worse, or it may lead to antibiotic-resistant infections that are much harder to treat. Taking all of the medicines is especially important for people who have an impaired immune system. They may be at an increased risk for a relapse because the original TB infection was never cured.
Surgery is rarely used to treat tuberculosis TB. But it may be used to treat extensively drug-resistant TB XDR-TB or to treat complications of an infection in the lungs or another part of the body. Surgery has a high success rate, but it also has a risk of complications, which may include infections other than TB and shortness of breath after surgery. Surgery sometimes may be needed to remove or repair organs damaged by TB in parts of the body other than the lungs extrapulmonary TB or to prevent other rare complications, such as:.
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