In infants who received a dose before 9 months, the vaccine was found to be safe and well-tolerated, according the pooled data. The authors concluded, "A large proportion of infants receiving MCV1 before 9 months of age are protected and the vaccine is safe, although higher antibody titres and vaccine effectiveness are found when MCV1 is administered at older ages.
Recommending MCV1 administration to infants younger than 9 months for those at high risk of measles is an important step towards reducing measles-related mortality and morbidity. The results of this analysis were presented to the WHO in , and they resulted in updated WHO recommendations on MCV administration at 6 months of age for infants at high risk of measles infection.
In the second analysis, the same group of researchers looked at the effect early vaccine dosing has on subsequent immune responses to the standard vaccine doses. This uncertainty "suggests that an early dose might decrease long-term protection because further doses were associated with reduced antibody titres and avidity," write Nicola Principi, MD, and Susanna Esposito, MD, both with the University of Milan, in an accompanying commentary on the two studies.
Ultimately, a three-dose vaccine schedule would be difficult and costly to implement, as the current two-dose schedule already sees poor adherences, Principi and Esposito conclude. A third dose of MCV administered in early infancy should be considered only in emergency situations, they add. Sep 20 Lancet Infect Dis immunogenicity and effectiveness study. Sep 20 Lancet Infect Dis subsequent doses study. Sep 20 Lancet Infect Dis commentary. A dose of the measles vaccine administered 6 through 11 months of age should not be counted as part of the standard, two-dose MMR series.
After an early dose of MMR vaccine administered at 6 through 11 months of age, the second dose should be at 12 to 15 months of age and the third dose should be administered at least 28 days after the second dose and can be administered up to 6 years of age. Children who already have received two doses of MMR vaccine at least a month apart, with the first dose given no earlier than the first birthday, do not need an additional dose when they enter school unless required by state law.
The recommendation that children receive a dose of MMR vaccine between years is not a hard-and-fast rule. It will be just as effective if the vaccine is administered as soon as 28 days after the preceding dose. For example, if your baby gets the first MMR dose at month wellness visit, you can ask your doctor to give the second dose at the month visit. That would complete the series, and your baby wouldn't need to receive another MMR shot before starting school unless required by state law.
Just be sure to save your immunization records. If your school system does require another shot just before kindergarten, and your child already received a second shot , don't panic; the additional "booster" dose will be safe. Depending on immunization laws in your state , your child may not be able to start school or college without proof he or she received two doses of measles, or has proof of having had measles.
A student who hasn't had either can be readmitted after receiving the first dose of MMR. In this situation, a second dose should be administered as soon as possible, but no sooner than 28 days after the first dose.
Some children may receive the measles, mumps, rubella and varicella MMRV vaccine , which adds protection against chickenpox. The second dose can also be given between ages 4 and 6 or at least 3 months after the first-standard dose. If all of this seems confusing, don't worry. Your pediatrician is a great resource for any information you need about measles and the vaccine.
Recommended Immunization Schedules. You may be trying to access this site from a secured browser on the server. Please enable scripts and reload this page. Turn on more accessible mode. Turn off more accessible mode.
When people with measles travel into the United States, they can spread the disease to unvaccinated people including children too young to be vaccinated.
From year to year, measles cases can range from roughly less than to a couple hundred. However, in some years, there were more measles cases than usual. In , people from 31 states were reported as having measles. Most of these people got measles in the United States after being exposed to someone who got measles while in another country. The Centers for Disease Control and Prevention, American Academy of Family Physicians, and American Academy of Pediatrics strongly recommend children receive all vaccines according to the recommended vaccine schedule.
Birth - 6 years schedule. Viewing discretion is advised. Skip directly to site content Skip directly to page options Skip directly to A-Z link. Vaccines for Your Children. Section Navigation. Facebook Twitter LinkedIn Syndicate.
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